Vitamin D3 100,000 IU/mL CHOLECALCIFEROL
Cholecalciferol, also known as vitamin D3, is a form of vitamin D that helps your body absorb calcium. It’s essential for maintaining healthy bones and a strong immune system [1][2].
Sources: It’s naturally synthesized in the skin when exposed to sunlight and can also be found in foods like fatty fish, beef liver, eggs, and cheese [2].
Uses: It’s commonly used as a dietary supplement to prevent or treat vitamin D deficiency, which can lead to conditions like rickets or osteomalacia [3].
Available to ship to your site 8-10 weeks after ordered
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10mL
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100,000IU/ml in grapeseed oil
Intramuscular Injection: Typically administered as an intramuscular shot, often in a healthcare setting [9].
Dosage: The dosage and frequency depend on the individual’s specific needs and medical advice [10]. -
Calcium and Phosphate Absorption: It enhances the absorption of calcium and phosphate from the small intestine [4].
Bone Health: It promotes the release of calcium from bones into the bloodstream, aiding in bone mineralization [4].
Renal Function: It helps in the reabsorption of phosphate in the kidneys [4].
It is hydroxylated in 2 steps into the active form calcitriol [2].
These actions collectively help maintain proper calcium and phosphate levels in the blood, which are vital for healthy bones and overall metabolic functions. -
Contraindications:
Allergic Reactions: Do not use if you have had an allergic reaction to vitamin D [1].
Hypervitaminosis D: Avoid if you have high levels of vitamin D in your body [1].
Hypercalcemia: Not recommended for individuals with high calcium levels in the blood [1].
Malabsorption Conditions: Conditions that impair nutrient absorption, such as Crohn’s disease or celiac disease, can affect how your body processes cholecalciferol [1].
Precautions:
Heart and Kidney Disease: Inform your doctor if you have a history of heart or kidney disease [1].
Electrolyte Imbalance: Conditions affecting electrolyte levels should be discussed with your healthcare provider [1].
Pregnancy and Breastfeeding: Consult a doctor before use, as dosage needs may vary during pregnancy or while nursing [1].
Allergies: Some formulations may contain ingredients like peanut or soybean oil, which could trigger allergic reactions [1]. -
Cholecalciferol (vitamin D3) can cause various side effects, ranging from common to severe. Here are some of the potential adverse reactions:
Common Side Effects
Gastrointestinal Issues: Nausea, vomiting, constipation, and stomach pain [1][5].
Headache: Some individuals may experience headaches [6].
Serious Side Effects
Hypercalcemia: High levels of calcium in the blood, which can cause symptoms like weakness, confusion, and abnormal heart rhythms [1][5].
Allergic Reactions: Symptoms can include rash, itching, swelling, severe dizziness, and trouble breathing [1][5].
Rare Side Effects
Hypercalciuria: High levels of calcium in the urine [1].
Hypersensitivity Reactions: Such as angioedema or laryngeal edema1.
Other Notable Side Effects
Loss of Appetite and Weight Loss: These can occur, particularly with higher doses [7].
Metallic Taste: Some individuals report a metallic taste in their mouth [3].
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Pregnancy:
Cholecalciferol (vitamin D3) is generally considered safe during pregnancy, but it should only be used if there is a clear need, such as a deficiency [1]. Here are some key points:
Dosage: It’s important to follow the recommended dosage, as excessive vitamin D can lead to hypercalcemia, which may cause complications [1].
Benefits: Adequate vitamin D levels are crucial for fetal development, particularly for bone health [1].
Breastfeeding:
Cholecalciferol is excreted into breast milk, and while it is generally safe, there are some considerations [1][6]:
Supplementation: Breastfed infants often require additional vitamin D supplementation, as breast milk alone may not provide sufficient amounts [8].
Monitoring: If the mother is taking high doses of vitamin D, the infant’s serum calcium levels should be monitored to avoid hypercalcemia [1]. -
Cholecalciferol (vitamin D3) should be stored properly to maintain its effectiveness. Here are some guidelines:
Temperature: Store at room temperature, away from heat and moisture [7].
Light: Keep it in a closed container, away from direct light.
Freezing: Do not freeze [5].
Children: Keep out of reach of children [7].
Expiration: Do not use outdated or no longer needed medicine. Consult your healthcare provider on how to dispose of it properly [5]. -
1. drugs.com 2. en.wikipedia.com 3. everydayhealth.com 4. medicine.com 5. mayoclinic.org
6. nhs.uk 7.medlineplus.gov 8. cdc.gov 9. druggenius.com 10. nhs.uk -
Cholecalciferol (vitamin D3) can interact with several medications, which may affect its absorption or increase the risk of side effects. Here are some notable interactions:
Major Interactions:
Digoxin: Increased risk of hypercalcemia, which can enhance the effects of digoxin and lead to serious heart issues1.
Thiazide Diuretics: These can increase the risk of hypercalcemia when taken with vitamin D [1].
Moderate Interactions:
Anticonvulsants: Medications like phenytoin and phenobarbital can reduce the effectiveness of vitamin D by increasing its metabolism [1].
Steroids: Corticosteroids can reduce calcium absorption, counteracting the effects of vitamin D [1].
Cholestyramine: This medication can decrease the absorption of vitamin D [3].
Minor Interactions:
Aluminum-containing Antacids: When taken chronically, these can increase aluminum levels in the blood, especially in patients with kidney disease [3].
Precautions:
Timing with Other Medications: Some medications can interfere with the absorption of vitamin D. It’s often recommended to take them at least 2 hours before or after taking cholecalciferol [1].
