Methylcobalamin [CD] 10mg/100mg/mL

30mL

Methylcobalamin injections can be administered either intramuscularly (into the muscle) or intravenously (into the vein) [1]. 

Methylcobalamin plays a crucial role in the body by supporting nerve health and function. Here’s how it works:
1. Myelin Production: Methylcobalamin is essential for the production of myelin, a substance that forms a protective sheath around nerve fibers. This myelin sheath is vital for proper nerve signal transmission [5][6].
2. Nerve Regeneration: It helps rejuvenate damaged neurons, promoting nerve repair and regeneration [5].
3. Methionine Synthesis: Methylcobalamin acts as a coenzyme in the synthesis of methionine from homocysteine, which is important for various cellular functions [7].
 

Allergy: Do not use methylcobalamin if you are allergic to vitamin B12 or cobalt [8][9].
Leber’s Disease: Individuals with Leber’s disease, a hereditary optic nerve atrophy, should avoid methylcobalamin as it can worsen the condition [8].
 

Metformin: Commonly used for type 2 diabetes, metformin can decrease the absorption of vitamin B12 [11].
Proton Pump Inhibitors (PPIs): Medications like omeprazole and esomeprazole, used to treat acid reflux and stomach ulcers, may reduce vitamin B12 absorption [1][11].
Chloramphenicol: This antibiotic can interfere with the hematologic response to vitamin B12 [1].
Colchicine: Used to treat gout, colchicine may decrease the absorption of vitamin B12 [12].
Aminosalicylic Acid: This drug, used for digestive issues, can also reduce vitamin B12 absorption [12].

Methylcobalamin is generally well-tolerated, but like any supplement, it can cause some adverse reactions in certain individuals. Here are some potential side effects:
Common Side Effects
Gastrointestinal Issues: Nausea, vomiting, diarrhea, and loss of appetite [13][6].
Headache: Some people may experience headaches [6][11].
Serious Side Effects
Allergic Reactions: Symptoms can include rash, itching, swelling (especially of the face, tongue, or throat), severe dizziness, and trouble breathing [1].
Dizziness: Severe dizziness or fainting can occur, particularly with injectable forms [1].

Pregnancy and Breastfeeding: Consult your doctor before using methylcobalamin if you are pregnant or breastfeeding [8][9].
Medical Conditions: Inform your healthcare provider about any existing medical conditions, especially if you have a history of liver disease or any other significant health issues [10].
Children: Do not give methylcobalamin supplements to children without medical advice [8][9].

Room Temperature: Keep it at room temperature, ideally between 20°C and 25°C (68°F to 77°F) [1][6].
Dry Place: Store it in a dry place, away from moisture and humidity [6].
Avoid Light and Heat: Protect it from direct light and heat [1].
Keep Away from Children: Ensure it is stored out of reach of children
For injectable forms refrigeration may be required.